Dr. Robert H. Keller founded The BIODORON Institute of Advanced Medicine in 1994. At the time this was considered a state-of-the-art medical clinic specializing in cutting edge treatment for immune system disorders and anti-aging.
Dr. Keller noticed a trend after reviewing subject lab results for years. He kept seeing significantly low levels of uric acid in subjects with immune disorders. His initial research concluded that uric acid is the last antioxidant at the body's disposal when all the normal antioxidants have been exhausted.
The one question that the doctor was looking for was since uric acid is the body's last defense... then what is the body's first defense? His investigation led him to a substance called glutathione. He discovered that glutathione is employed by every organ in the human body to be the most prevalent, powerful and multifunctional antioxidant.
Glutathione (GSH) is a small protein produced naturally in our cells if the requisite precursors are present. It functions both as an antioxidant and an antitoxin and is a major defense system against illness and aging. Our glutathione level actually indicates our state of health and can predict longevity. There are over 60,000 medical articles currently published on GSH, yet most health professionals have only a vague idea of its significance. Dr. Keller believes that in the near future the importance of glutathione will be widely recognized.
The good doctor needed to test the hypothesis that the levels of GSH were severely diminished in subjects with immune disorders. He knew the test must measure GSH inside of the lymphocytes (activated cells) to get a current and accurate gauge of a subject's GSH level.
And this is why along with his team of scientists he developed a proprietary lab test to measure levels of GSH inside the lymphocytes. The tests confirmed the hypothesis. People who are stressed, aging, lacking sleep, or with any prolonged illness utilize glutathione at an accelerated rate resulting in decreased bodily stores, weakened defenses, and increased risk of illnesses including accelerated aging.
It was clear that the GSH levels needed to be replenished in these subjects. But how? Glutathione is produced naturally from three amino acids: glycine, glutamine, and cysteine. These essential precursors of GSH must be able to make it from the mouth to the gut, and then through the cell walls and subsequently the mitochondrial membrane.
Our digestive system is truly a marvel of God's handy work. Every hour a wonderful spectacular arrangement of many pipes and funnels are at work in perfect harmony... as they usher our food through our body and distribute the nutrients where they need to go. This fantastic complicated system runs on its own track and just motors along without even a conscious thought from us. However, in today's world is that enough? Are we eating real food and in the right amounts and from the right soil?
Unfortunately, we can't raise our body's GSH level with ordinary foods or pure L-glutathione. Even though glutathione is present in many fruits, vegetables and meats... this protein is instantly broken down during digestion into its three amino acids. Cysteine or N-acetylcysteine (NAC) is the most important of these precursors and is the main limiting factor necessary for the body to manufacture GSH. Alone in the gut after digestion, cysteine is treated as a free radical and rapidly oxidized, and therefore only a very small percentage reaches our bloodstream and cells.
Furthermore, GSH is always in great demand and is rapidly consumed, so any GSH that is made will be used up quickly making it even more difficult to increase the level of glutathione in the body. So what Dr. Keller was able to do is develop a product that contains the necessary components of glutathione. When this product is absorbed into the body it can help stimulate the body's own production of glutathione. And Dr. Keller believes that every cell in the human body can benefit from the increased levels of this very important antioxidant.
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